Brucellosis is a highly contagious disease found worldwide. It is also known as Malta Fever, Gibraltar Fever, Mediterranean Fever, Bang’s Disease and many others. The names frequently came from the areas where it was identified as a pathogenic disease and in relationship to people that first were found to have the symptoms or people that attempted to treat them. The correlation between the cause and symptoms was first made by David Bruce, where it derives its current name. Strains of the Brucella bacteria are found in various domestic animals including cattle, pigs, goats and
Sjögren’s Syndrome is a disease of specific excretory glands, generally the salivary and lacrimal glands. These glands are responsible for the production of saliva and tears. It manifests itself as a chronic autoimmune disease characterized by the symptoms of dry mouth and dry eyes. Basically the white blood cells infiltrate these exocrine glands resulting in inflammation. The inflammatory process causes damage to the glands and they can cease to function (1). Frequently Sjögren’s Syndrome accompanies other autoimmune diseases such as Rheumatoid Arthritis and Lupus (2). Sjögren’s syndrome may cause skin, nose, and vaginal dryness, and may affect other organs of the body, including the kidneys, blood vessels, lungs, liver, pancreas, peripheral nervous system (distal axonal sensorimotor neuropathy) and brain(1). Causes of Sjögren’s Syndrome are suspected to primarily stem from genetic, environmental, inflammatory (such as from a severe illness) and/or hormonal triggers. Oxidative stress has been noted to be a possible biomarker and may be a useful tool in the diagnosis of the disease (3), Evidence exists to support the fact that inflammatory conditions from oxidative stress result in the lack of ability of neurotransmitters to stimulate glandular function (4)(5). Traditional management of the disease depends upon the severity. Mild cases may be able to be controlled with eye drops and/or more frequent sipping of water. Severe cases may require surgery and/or medications for relief. While there is no known medical cure, as in other autoimmune diseases the disease is known to have specific ties to excessive oxidative stress (4)(6)(7)(8)(9) and this may be a key to understanding the disease and eliciting some form of remission, control or cure. Oxidative stress can come from numerous causes and can also result in various other illness conditions. Sjögren’s Syndrome presents a novel opportunity for a natural wellness product like ASIHW Essential Proteins. ASIHW Essential Proteins offers direct precursors to assist the body of low antioxidant individuals in building glutathione. This would boost and support the antioxidant status of that individual, relieving the inflammatory process and allow the nervous system and affected glands to function normally again. Glutathione is also important for the immune system (10). This would normalize the immune system function of an individual suffering from an autoimmune disease. It might also boost the immune system of individuals that might be low in antioxidant capacity and help them be more resistance toward getting this illness in the first place (glutathione levels drop as we age or are exposed to dietary, emotional and physical stressors that can cause free radicals and oxidative stress). Since oxidative stress results in toxins in the body, many of these toxins are causal in the painful inflammation and symptoms related to the illness, and glutathione is supportive in removing/neutralizing these free radical toxins. References: (1) Sjögren’s Syndrome – Wikipedia http://en.wikipedia.org/wiki/Sj%C3%B6gren%27s_syndrome (2) Sjögren’s Syndrome – Mayo Clinic http://www.mayoclinic.org/diseases-conditions/sjogrens-syndrome/basics/definition/con-20020275 (3) Possible involvement of oxidative stress in salivary gland of patients with Sjogren's syndrome http://www.ncbi.nlm.nih.gov/pubmed/17314496 (4) Effect of Oxidative Stress on Secretory Function in Salivary Gland Cells http://cdn.intechopen.com/pdfs/36264/InTech-Effect_of_oxidative_stress_on_secretory_function_in_salivary_gland_cells.pdf (5) Impaired Neurotransmitter Release from Lacrimal and Salivary Gland Nerves of a Murine Model of Sjögren's Syndrome http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241007/ (6) Evaluation of Lipid Oxidative Stress Status in Sjögren Syndrome Patients http://iovs.arvojournals.org/article.aspx?articleid=2188564 (7) Sjøgren's syndrome-associated oxidative stress and mitochondrial dysfunction: prospects for chemoprevention trials http://www.ncbi.nlm.nih.gov/pubmed/23153390 (8) Oxidative Stress to the Cornea, Changes in Corneal Optical Properties, and Advances in Treatment of Corneal Oxidative Injuries http://www.hindawi.com/journals/omcl/2015/591530/ (9) Oxidative stress in the pathogenesis of diffuse lung diseases: A review http://www.sciencedirect.com/science/article/pii/S0954611109001279 (10) Glutathione: Your Key to Health – Dr. Jimmy Gutman http://www.asihw.com/products/details/3/glutathione-your-key-to-health
Cancer has become a pandemic in developing countries. In the USA one in three women (1 out of 3) and one in two men (1 out of 2) will be diagnosed with cancer in their lifetime. Yet in 1900, barely a century ago, only one in thirty-three (1 out of 33) were diagnosed with cancer! Sadly, individuals finding themselves (or friends or family) facing cancer seldom know about or understand the various options that may be available to avoid or survive cancer, and to live a long and healthy life without cancer.
Many neurological and Psychiatric disorders are difficult to diagnose and treat without the use of extensive therapy or somewhat invasive drugs (with their potential side effects). However, low levels of glutathione have been associated with many neurodegenerative disorders, including many psychiatric disorders(1)(2)(3)(4)5(5)(6). While glutathione itself does not cross the blood-brain barrier, the precursors can and do cross it(2). Synthetic forms of one of the precursors
What is Oxidative Stress in our body? Oxidative stress is caused by the presence of any of a number of reactive oxygen species (ROS) which the cell is unable to counterbalance. These reactive oxygen species are toxic to the body(2).The result is damage to one or more biomolecules including DNA, RNA, proteins and lipids. Oxidative stress has been implicated in the natural aging process as well as a variety of disease states.